Manage a thyroid condition with a structured daily plan. Covers understanding your diagnosis, medication protocols, lab monitoring, diet considerations, symptom tracking, and working effectively with your endocrinologist.
Know whether you have hypothyroidism or hyperthyroidism and the underlying cause
Hypothyroidism (underactive thyroid) affects 5% of Americans and is most commonly caused by Hashimoto's thyroiditis, an autoimmune condition. Symptoms include fatigue, weight gain, cold intolerance, dry skin, and brain fog. Hyperthyroidism (overactive thyroid) affects 1% of Americans and is most commonly caused by Graves' disease. Symptoms include weight loss, rapid heartbeat, anxiety, heat intolerance, and tremors. Your diagnosis determines your treatment plan.
Understand your key lab values: TSH, Free T4, Free T3, and thyroid antibodies
TSH (thyroid-stimulating hormone) is the primary screening test. Normal range: 0.4-4.0 mIU/L, though many endocrinologists target 0.5-2.5 mIU/L for optimal well-being. Free T4 (normal: 0.8-1.8 ng/dL) measures the active hormone your thyroid produces. Free T3 (normal: 2.3-4.2 pg/mL) measures the most active form. Thyroid antibodies (TPO, TgAb) confirm autoimmune thyroid disease. Ask your doctor for copies of every lab result and track them over time.
Find an endocrinologist or thyroid specialist if your primary care doctor manages only with TSH
Primary care doctors often test only TSH and prescribe based on that single number. An endocrinologist tests the full thyroid panel (TSH, Free T4, Free T3, antibodies), considers symptoms alongside lab values, and is more experienced with medication adjustments. Most insurance plans cover endocrinology visits with a referral. Wait times for new patient appointments average 4-8 weeks, so book early. Appointments cost 150-350 USD without insurance.
Medication Management
Take thyroid medication at the same time every day on an empty stomach
Levothyroxine (Synthroid, Levoxyl, generic) is the standard treatment for hypothyroidism. Take it first thing in the morning, 30-60 minutes before eating or drinking anything other than water. Coffee reduces absorption by 36%. Calcium and iron supplements reduce absorption by 40-65% and should be taken 4 hours apart from thyroid medication. Consistency in timing matters more than the specific time chosen.
Do not switch between brand-name and generic without consulting your doctor
Different manufacturers of levothyroxine can vary by up to 12% in potency, which is enough to affect your levels. If your pharmacy switches your generic manufacturer, your TSH may shift. Some patients feel better on brand-name Synthroid or Tirosint (a gel cap with fewer fillers). If you are stable on a specific manufacturer, ask your pharmacist to note it in your file. Insurance typically covers generic (10-30 USD per month) and may require prior authorization for brand (50-150 USD per month).
Know the symptoms of overmedication and undermedication
Undermedication symptoms: persistent fatigue, weight gain, constipation, depression, dry skin, and feeling cold. Overmedication symptoms: anxiety, insomnia, rapid heartbeat, tremors, diarrhea, and unintentional weight loss. If you experience these symptoms between lab checks, contact your doctor rather than waiting for your next scheduled appointment. Dose adjustments are typically made in small increments of 12.5-25 mcg at a time with lab rechecking 6-8 weeks after each change.
Lab Monitoring Schedule
Get labs drawn every 6-8 weeks when adjusting medication, every 6-12 months when stable
During dose adjustments, labs should be drawn 6-8 weeks after any medication change because it takes that long for levels to stabilize. Once your dose is stable and you feel well, testing every 6-12 months is sufficient. Always get labs drawn at the same time of day (morning is standard) and before taking your medication that day. This ensures comparable results across tests. Thyroid panels cost 50-150 USD without insurance.
Request a full thyroid panel, not just TSH, at least once per year
TSH alone does not tell the full story. Free T4 shows how much hormone your thyroid is producing. Free T3 shows the active hormone available to your cells. Some patients have a normal TSH but low Free T3 due to poor T4-to-T3 conversion. If your TSH is normal but you still feel symptomatic, Free T3 and T4 levels provide additional information. Thyroid antibody levels tracked annually show whether autoimmune activity is increasing, stable, or decreasing.
Track your lab results in a spreadsheet or health app over time
Create a simple spreadsheet with columns for date, TSH, Free T4, Free T3, antibodies, medication dose, and how you feel. This long-term tracking reveals patterns your doctor may miss in a single visit. Apps like Medisafe or MyTherapy can track both medication adherence and lab results. Bring your tracking history to every appointment. Patients who actively track their labs report better symptom management and more productive doctor visits.
Diet and Lifestyle Considerations
Maintain consistent iodine intake and avoid mega-doses of iodine supplements
Your thyroid needs iodine to produce hormones, but both too little and too much iodine can worsen thyroid conditions. Most Americans get adequate iodine from iodized salt and dairy products. Avoid kelp supplements and high-dose iodine supplements (over 150 mcg per day) as they can trigger thyroid flares in Hashimoto's patients. One teaspoon of iodized salt provides 284 mcg, which meets the daily recommended intake of 150 mcg.
Eat selenium-rich foods to support thyroid function
Selenium is essential for converting T4 to T3 (the active thyroid hormone). Brazil nuts are the richest source: just 1-2 nuts per day provide 70-140 mcg, meeting the daily recommendation of 55 mcg. Other sources include tuna, sardines, eggs, and sunflower seeds. Multiple studies show that 200 mcg of selenium daily reduces thyroid antibodies in Hashimoto's patients by 20-40% over 6-12 months. Do not exceed 400 mcg daily as excess selenium is toxic.
Exercise regularly to improve thyroid hormone sensitivity and manage symptoms
Moderate exercise (30 minutes, 5 days per week) improves T3 utilization at the cellular level, reduces fatigue, supports healthy weight maintenance, and improves mood. Start with low-impact activities (walking, swimming, yoga) if fatigue is a major symptom and gradually increase intensity. Intense exercise can temporarily elevate cortisol, which may suppress thyroid function, so avoid overtraining. Most thyroid patients see the best results with moderate, consistent exercise rather than intense, sporadic workouts.
Long-Term Management
Recheck thyroid levels after major life changes
Pregnancy, menopause, significant weight changes (gain or loss of 10+ lbs), starting or stopping estrogen-containing medications, and major surgeries can all shift thyroid hormone needs. Pregnant women with hypothyroidism typically need a 30-50% dose increase in the first trimester. Notify your endocrinologist of any major life change and request lab work 4-6 weeks afterward to determine if a dose adjustment is needed.
Get a thyroid ultrasound as recommended by your doctor
Thyroid ultrasounds detect nodules (found in 50-60% of adults over 60), monitor existing nodules for growth, and assess thyroid size. Your doctor may recommend an initial ultrasound at diagnosis and follow-ups every 1-2 years if nodules are present. Nodules larger than 1-1.5 cm or with suspicious features may require a fine-needle aspiration biopsy to rule out thyroid cancer. Ultrasounds cost 100-500 USD and are typically covered by insurance with a diagnosis code.
Build a support network and educate yourself from reliable sources
Thyroid conditions are lifelong for most people. Reliable information sources include the American Thyroid Association (thyroid.org), your endocrinologist, and peer-reviewed studies. Avoid social media thyroid advice that promotes unproven supplements or encourages stopping medication. Online support communities (Inspire Thyroid community, r/Hypothyroidism) connect you with others managing the same condition. Consider joining a local or virtual support group, especially in the first year after diagnosis. This guide is informational only, not medical advice.
Frequently Asked Questions
Can thyroid conditions be cured?
Most thyroid conditions are managed, not cured. Hashimoto's thyroiditis and Graves' disease are autoimmune conditions that typically require lifelong management. Hypothyroidism from Hashimoto's is treated with daily thyroid hormone replacement. Hyperthyroidism from Graves' disease may be treated with anti-thyroid medication (some patients achieve remission after 12-18 months), radioactive iodine ablation, or surgery. Post-surgical or post-ablation patients take levothyroxine for life.
What foods should I avoid with a thyroid condition?
Soy products in large amounts (more than 25g soy protein daily) may interfere with thyroid hormone absorption if taken within 4 hours of medication. Cruciferous vegetables (broccoli, kale, cauliflower) contain goitrogens but are safe when cooked and eaten in normal amounts. Gluten-free diets may benefit some Hashimoto's patients (Hashimoto's and celiac disease co-occur in 2-5% of cases), but this is not universal. The most important dietary rule is consistency in iodine intake and proper timing of medication away from food.
Why do I still feel tired even though my TSH is normal?
Several possibilities exist. Your Free T3 may be low even with normal TSH (poor T4-to-T3 conversion). Your optimal TSH may be lower than the lab reference range, which goes up to 4.0 but many patients feel best between 0.5-2.0. You may have co-existing conditions (iron deficiency, vitamin D deficiency, sleep apnea) contributing to fatigue. Or your medication dose may need fine-tuning. Request a full panel including Free T3, check iron and vitamin D levels, and discuss your symptoms honestly with your endocrinologist.
How does pregnancy affect thyroid conditions?
Pregnancy increases thyroid hormone demand by 30-50%, particularly in the first trimester when the fetus depends entirely on maternal thyroid hormone for brain development. Women with hypothyroidism should have TSH checked as soon as pregnancy is confirmed and every 4 weeks through the first trimester. The target TSH during pregnancy is below 2.5 mIU/L. Untreated maternal hypothyroidism is associated with increased risk of miscarriage, preterm birth, and impaired fetal neurodevelopment.